Rheumatoid Arthritis Quiz

Flat bones of the cranium develop by which process?

A) Endochondral ossification
B) Enchondral mineralization
C) Intramembranous ossification
D) Primary spongiosa formation

Your Answer (0-5):

What percentage of body weight does the adult skeleton account for?

A) 8%
B) 12%
C) 15%
D) 20%

Your Answer (0-5):

#3. Rheumatoid nodules are histologically characterised by:

1. Multinucleate giant cells surrounding urate crystals
2. Caseating granulomas with Langhans cells
3. Central necrosis rimmed by palisaded histiocytes
4. Fibrinoid necrosis with neutrophilic infiltrate

Your Answer (0-5):

Approximately 10% of the skeleton is remodelled annually. If a person lives to 70 years after skeletal maturity (achieved at age 20), how many complete turnovers of the entire skeleton will theoretically occur?

Your Answer :

#2. The destructive granulation tissue that grows over articular cartilage in rheumatoid arthritis, eventually causing fibrous ankylosis, is called:

1. Tophus
2. Pannus
3. Peel
4. Rind

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Osteoclasts are derived from which cell lineage?

A) Mesenchymal stem cells
B) Osteoblasts
C) Circulating monocytes
D) Fibroblasts

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#4. What is the prevalence (%) of rheumatoid arthritis in India approximately?

You don't have to write the % sign. Input just the numeral.

Your Answer :

Which signaling molecule acts as a "decoy" receptor, blocking RANKL from activating osteoclast precursors?

A) M-CSF
B) NF-κB
C) Osteoprotegerin (OPG)
D) RANK

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The hardness of bone matrix is imparted by which inorganic compound?

A) Calcium carbonate
B) Hydroxyapatite
C) Tricalcium phosphate
D) Fluorapatite

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Which type of bone has haphazard collagen arrangement and is always abnormal in adults?

A) Lamellar
B) Cortical
C) Woven
D) Cancellous

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