ONE PYQ

#41. Which one of the following causes low-volume erythrocytosis?
(a) Polycythemia Rubra Vera
(b) Exogemus testosterone therapy
(c) Gaisbock\'s syndrome
(d) High altitude

#42. First line therapy in chronic phase of chronic myeloid leukemia is
(a) Rituximab
(b) Thalidomide
(c) Imatinib
(d) Chlorambtucil

#43. With regard to management of idiopathic thrombocytopenia purpura, consider the following statements:
I. All patients with ITP with platelet count less than I00x10^9/L should receive high dose of glucocorticoids
II. For patient with spontaneous bleeding, 40 mg of dexamethasone daily is indicated for 4 days
III. Intravenous immunoglobulin can raise the platelet count
IV. Life threatening bleeding should be treated with platelet transfusion

Which of the following statements given above are correct ?
(a) I, Il and Ill
(b) Il, III and IV
(c) I, Ill and IV
(d) I, II and IV

#44. Which of the following drugs can cause secondary weight gain wing?
I. Insulin
II. Propranolol
III. Orlistat
IV. Thyroxine

Select the correct answer using the code given below :
(а) I, II and IV
(b) I and Ill
(c) II, III and IV
(d) I and Il only

#45. Under which one of the following conditions, the НРА axis suppression is likely to result in crisis due to adrenal insufficiency following withdrawal of glucocorticoids?
(а) If glucocorticoids have given bу intravenous route for five days
(b) If glucocorticoids have Ьееn administered orally for one week
(с) If glucocorticoids have Ьееn prescribed гереаtedly within previous уеar
(d) If the dose is less than equivalent of 5 mg prednisolone рет day

#46. Wilson\'s disease has which of the following inheritance?
(а) X-Iinked recessive
(b) Autosomal dominant
(с) Autosomal recessive
(d) It is an acquired disease

#47. Which of the following сап bе used for management of severe hyperkalaemia?
I. Intravenous calcitonin
II. Intravenous sodium bicarbonate
III. Oral sodium polystyrene sulphate
IV. Intravenous calcium gluconate

Select the correct answer using the code given below:
(а) I, II and IV
(b) Il, III and IV
(с) I and Il only
(d) I and IV only

#48. Which опе of the following conditions сап сause euvolaemic hyponatraemia?
(а) Adrenocortical failure
(b) Hypothyroidism
(с) Nephrotic syndrome
(d) Вurns

#49. Which one among the following vectors transrnits the filaria Loa Loa?
(a) Simulium
(b) Chrysops
(c) Cyclops
(d) Culicoides

#50. Which of the following is the most favourable prognostic parameter in Bell\'s palsy ?
(a) Incomplete paralysis in the first week
(b) Mild CSF lymphocytosis
(c) Denervation in EMG after 10 days
(d) Pain behind the ear

#51. Which of following drugs is ineffective against gram positive bacteria?
(a) Monobactams
(b) Glycopeptides
(c) Fluoroauinolones
(d) First generation cephalosporins

#52. Which one of the following statements is correct regarding leprosy?
(a) Type 1 Leprosy Reaction is also called erythema nodosum leprosum
(b) Type 2 Leprosy Reaction is an immune complex mediated syndrome called arthus phenomenon
(c) \'Leon face\' appearance is seen in tuberculoid leprosy
(d) Nose is the last site of involvement in lepromatous leprosy

#53. A 56 old gardener presents with an ulcerative nodule with purulent discharge on his right index finger. He had a prick with a thorn, at the same site a month back. Which one of the infections is most likely?
(a) Chromoblastomycosis
(b) Mycetoma
(c) Phaeohyphomycosis
(d) Sporotrichosis

#54. A 36 year old man presents with decreased appetite, mouth soreness, diarrhoea and irritability. On examination he has a bright red tongue with a pigmented scaly around the neck.
Which one of the following food items in his diet has a bearing on his disease?
(a) Rice
(b) Wheat
(c) Corn
(d) Fish

#55. Acrodermaitis enteropathica is an autosomal recessive metabolic disorder which affects the absorption of which one of the following micronutrients?
(а) Iodine
(b) Zinc
(с) Iron
(d) Selenium

#56. Consider the following statements with regard to the treatment of vitmin А deficiency:
I. Repeated high doses of retinol can cause liver damage and teratogenecity.
II. Acute overdose of vitamin А mау lead to increased intracranial pressure аnd skin desquamation
III. Regular vitmnin А supplementation is аlso recommended for pregnant women even in countries where vitamin А defciency is not endemic
IV. Excessive intake of carotene mау саuse harmless огаngе pigmentation of the skin

Which of the statanents given above correct?
(а) I, II and III
(b) I, Il and IV
(с) I, Ill and IV
(d) II, III and IV

#57. Коebnег phenomenon is in which оnе of the following conditions?
(а) Psoriasis
(b) Асnе Vulgaris
(с) Bechet\'s disease
(d) Leprosy

#58. Consider the following regarding human hair growth сусle :
I. Апаgеп is а phase of active hair growth
II. Теlogеп is а transitional phase
III. Catagen is а resting phase

Which of the statements given above is/are correct ?
(а) I оnlу
(b) III only
(с) I and II only
(d) I, Il and Ill

#59. Consider the following statements regarding oculocutaneous albinism:
I. The disease results from genetic abnormalities leading to destruction of melanocytes
ll. Type 1 albinism is due to a defect in the tyrosinase gene
III. Patients may present with poor vision, rotator nystagmus and alternating strabismus
IV. Patients are at increased risk of sunburn or developing skin cancer

Which of the statements given above correct?
(а) I, II and III
(b) I, Il and IV
(с) I, Ill and IV
(d) II, III and IV

#60. A 42 year old man presented with recurrent oral ulcers since one year, episodes of redness of eye and genital ulcers. Which one of the following tests is of diagnostic value?
(a) Mantoux test
(b) Drug-sensitivity test
(c) Pathergy test
(d) Patch test