Lectus

A 28-year-old man presents with a 1-week history of penile discharge. He reports painful urination in the mornings, and sometimes feels a lingering pain in his genital region throughout the day. He denies any fever, body aches, or joint pains. Past medical history is insignificant, and he does not take any medications. When asked about social history, he reports frequent intercourse with women he meets in bars and does not always remember to use a condom. Physical exam reveals a thick yellow penile discharge, which is collected and sent for analysis. Ceftriaxone is administered intramuscularly and the patient is sent home with a prescription for an oral medication. Which of the following oral drugs was most likely prescribed?Deselect Answer

A large pharmaceutical company is seeking healthy volunteers to participate in a drug trial. The drug is excreted in the urine, and the volunteers must agree to laboratory testing before enrolling in the trial.
The laboratory results of one volunteer are shown below:

×××
Urinalysis test results:

×××
Assuming a urine flow rate of 1 mL/min, which set of values represents the renal clearance of glucose, sodium, and creatinine in this patient?Deselect Answer

A 13-year-old obese male presents with a two-month history of progressive right hip pain and limping. Physical examination reveals restricted internal rotation and abduction of the right hip. X-ray demonstrates posterior and inferior displacement of the femoral epiphysis relative to the femoral neck. He undergoes surgical fixation of the slipped capital femoral epiphysis (SCFE). During the procedure, the surgeon is particularly cautious about preserving certain vascular structures to prevent avascular necrosis (AVN). Which of the following blood vessels provides the primary blood supply to the femoral head that is most at risk in this patient?Deselect Answer

A 58-year-old construction worker presents to his physician with a 3-year history of progressive thickening and contracture of his right palm. He reports difficulty fully extending his ring and little fingers, which have gradually curled inward toward his palm. The patient denies any history of trauma to his hand but notes that his father had a similar condition. Physical examination reveals a firm, nodular thickening of the palmar fascia with palpable cords extending toward the affected digits. The ring finger shows a 30-degree flexion contracture at the metacarpophalangeal joint. A biopsy of the affected palmar fascia is performed, revealing increased cellularity with spindle-shaped cells that stain positive for smooth muscle actin. Which of the following best describes the primary cellular mechanism underlying the pathogenesis of this patient's condition?Deselect Answer